Muhammad Salman Sanie Smeer

Project: Biosynthesis of Gold Nanoparticles (AuNP) from Red Ginger Extract for Anticancer Applications.

• Conducted advanced material characterization, including UV-Vis spectroscopy, SEM, FTIR, and XRD, to analyze the morphology, stability, and functional groups of the synthesized nanoparticles.
• Optimized synthesis parameters such as pH, reaction time, and extract concentration to achieve desired nanoparticle properties.
• Evaluated the anticancer potential of the nanocomposite through preliminary in vitro studies.
• Collaborated with multidisciplinary teams to analyze results and prepare reports for publication.

Project: Molecular Docking and Simulation Study of Stevioside Against Monkeypox Virus Target Protein

• Conducted molecular docking simulations to evaluate the interaction between stevioside and monkeypox virus target protein (PDB ID: 4QWO).
• Utilized computational tools such as PyRx and AutoDock Vina to predict binding affinities and analyze docking poses.
• Performed protein preparation, ligand optimization, and active site identification to ensure docking accuracy.
• Interpreted docking results and visualized binding modes using software such as Chimera and Discovery Studio.
• Compiled findings into comprehensive reports and presented them to the research team for discussion.

Project: Donapezil-Loaded Bovine Serum Albumin Nanoparticles for Alzheimer’s Intranasal Treatment

• Participated in a brief research project as part of the IISMA program, focusing on the development of nanoparticle-based drug delivery systems for Alzheimer's treatment.
• Investigated the formulation of Donapezil-loaded bovine serum albumin (BSA) nanoparticles for improved intranasal delivery.
• Collaborated with researchers in designing strategies to enhance drug bioavailability and crossing of the blood-brain barrier.
• Gained insights into the interdisciplinary approach of pharmaceutical nanotechnology through hands-on experience in a global research setting.